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Ribo-Zest™  can be used daily to nutritionally support healthy energy levels for heart and muscle tissue. Ribo-Zest™ increases cardiac efficiency, lowers exercise-related stress, and increases athletic performance while reducing muscle fatigue, cramping, and soreness.

Item # Product Size
819 Ribo-Zest 15 Servings


Useful nutrients for individuals requiring high levels of cellular energy to improve their quality of life.†
Helps restore ATP in cardiac and skeletal muscle and improves antioxidant balance.†

Supplies clinically significant amounts of BioEnergy Ribose, fruit and vegetable derived antioxidants, branched chain amino acids, glutamine and chromium.†

Research & Education
The metabolism of D-ribose in man Restitution of myocardial adenine nucleotides: acceleration by administration of ribose

Product Details†

The Ribo-Zest® Program Clinically shown to:
- Improve Antioxidant Balance
- Enhance Ability to Exercise
- Reduce Muscle Fatigue
- Improve Heart Function
- Restore Heart Energy

Who will benefit from Ribo-Zest®?
- Patients requiring increased cardiac energy and efficiency;
- Individuals requiring high levels of cellular energy to improve their quality of life;
- Athletes wishing to increase athletic performance and improve recovery;
- Individuals who wish to reduce post exercise muscle fatigue;
- Athletes who want to lower oxidative stress during and after exercise;
- Individuals requiring ATP replenishment of cardiac and skeletal muscle.

How long can Ribo-Zest® be used?
- Ribo-Zest is safe to use as directed on a daily basis by individuals requiring ongoing nutritional support. When should Ribo-Zest® be consumed?
- Ribo-Zest may be consumed once or twice daily. Many individuals have reported
increased endurance and improved recovery by taking one serving before and one serving just after exercise.



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the full Clinician's Resource Paper
and ingredients

Ribo-Zest® Key Ingredients

D-Ribose: The Role of D-Ribose in the Body
D-ribose is a naturally occurring 5-carbon monosaccharide. D-ribose is used to synthesize nucleotides (DNA and RNA), nucleic acids, glycogen and other important metabolic products. Ribose is formed naturally in the body from the conversion of glucose via the pentose phosphate pathway or also known as the hexose monophosphate shunt. Supplemental ribose through its intermediate ribose-5-phosphate is the substrate for the formation of 5-phospho-ribose-1-pyrophosphate (PRPP) (1)

The importance of Ribose to cardiac and skeletal muscle biochemistry
Supplemental ribose plays a vital role in both myocardial and skeletal muscle metabolism, primarily through its participation in the synthesis of ATP from PRPP, adenine nucleotides and nucleic acid synthesis, cyclic nucleotide metabolism and energy transfer reactions (2). In these tissues, the hexose monophosphate shunt is insufficient due to low availability of glucose-6-phosphate dehydrogenase (3). When ribose is supplemented, the rate-limiting step glucose-6-phosphate dehydrogenase is bypassed, thereby elevating the level of PRPP, which increase adenosine nucleotide biosynthesis and accelerates ATP replenishment of cardiac and skeletal muscle (4).

Mixing ribose and fructose
The proprietary mixture of ribose and fructose supports ATP replenishment from glycolysis, the hexose monophosphate
shunt and the sugar shuffle, the interconnection between glycolysis and the hexose monophosphate shunt is shown in (Figure 1). The entry of fructose and ribose into cells is not insulin dependent. In addition, fructose is an
extremely poor elicitor of insulin secretion (5).

Antioxidant support
Thirty years ago who would have thought that the term “antioxidant” would have become virtually a household word. Well, it has and today there are so many products touting their “antioxidant capacity” that it is downright confusing. Patients often ask which antioxidant(s) is (are) best for me and how do antioxidants compare with each other? Enter ORAC. The ORAC (Oxygen Radical Absorbance Capacity) assay was developed in part at the USDA and provides a means by which different antioxidant compounds or groups of compounds can be assessed for their ability to quench free radicals. Moreover, the ORAC measurement yields a single number referred to as the ORAC value based on the degree to which an “antioxidant” can inhibit the action of free radicals as well as the time it takes to do it (6). The ... Click here to continue reading

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†These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.